Ryu
Advantage to a Ryu player who is perfect at his anti-airs. However that's difficult for Ryu. Sakura gets it back on the ground so ultimately this is about even.

Ken
Footies are completely different from the Ryu match. Don't like the guessing game after he hits EX Tatsumaki. Also forward kick (step kick?) and hit-confirm Shoryukens make the match difficult. Can't back dash his Shoryuken. Feel like it's a slight disadvantage for Sakura.

Chun
Chun's footies and backdash are difficult to deal with. However Chun has difficulty dealing with Sakura's jump-ins. Chun wins in footsies, but Sakura deals more damage. It's a tough fight but only a slight disadvantage for Sakura.

Honda
The key is how many of her poor-performance Hadokens Sakura can fire off. Honda can push Sakura in the corner if she doesn't take him serious. Don't bother fighting if you can't take down his neutral and forward jumps with DP. A disadvantage fight for her, but I don't have a losing record against any Hondas so I'll call this even.

Blanka
Fight this on the ground. Blanka's s.mp is troublesome. A disadvantage fight for her, but I don't have a losing record against any Blankas so I'll call this even.

Zangief
I've fought this fight a lot, and after talking it out with Cantona I'll call it even. I don't think Sakura wins this, but if Zangief's step up this game it could go in his favor. For now it's even.

Guile
A rough fight. Even if you keep up with him he can just wear you down. You have to use RH and EX HK to get in, stay in, and finish it. Sakura will never have an advantage in this fight no matter how hard you work.

Dhalsim
As a mountain hermit (is he referring to a player name here maybe?) once said this is advantage Dhalsim. Sakura has to take risks to get in. And he's got his anti-airs covered. Sak can never have an advantage in this fight.

Balrog
I think this is fairly even. They can both do what they do well against each other. Balrog can't run away from Sak's wake up game, so that's nice.

Vega
She's at a complete disadvantage in footsies against him, but if Sak gets in she can take advantage of his poor defenses. I'd call this disadvantage Sak, but again there are no Vega's I have a losing record against so I'll call this even.

Sagat
Finish your combos with Sakura Otoshi for great set-ups and big damage - advantage Sak. Of course she loses when she can't get in.

Bison
This is rough. Scissor Kick pressure of course, as well as MK and his set-ups off throws are difficult to read. Bison has problems dealing with her jump-ins, but overall I'd say Bison has a solid advantage.

Viper
It's hard for Sak and her poor defenses to change things up with Viper on the offense. If she gets knocked down she can lose the whole match. And it's hard to catch a runaway Viper. This is definitely advantage Viper, and a big one at that.

Rufus
Advantage Sak on the wakeup game and her damage output. If you do it right EX Messiah is nothing to worry about. A lot of people hate this fight, but if you get used to it it's pretty fun. This is possibly the most fun fight for Sakura.

Fuerte
Both characters don't like getting caught in each other's traps. I don't really have a gameplan against him, but I don't have a losing record against any Fuerte's so I'll call this advantage Sak. I like fighting against Fuerte.

Abel
This one's hard. For both I think. But I don't have a losing record against any Abel's so I'll say slight advantage Sak.

Akuma
This asshole's disadvantage Sak. He nullifies everything that's good about Sak! He's got great set ups from Demon Flips, unblockables, and great offense and defense. This guy's a pain. He's definitely in Sak's worst 5 matches.

Seth
Definitely disadvantage Sak. But if you land one big combo against him you have a chance. Footsies don't work against him so she'll never have an advantage against him.

Cammy
Don't think she has an advantage against her. Like Viper, get knocked down once and that can be the whole match. Sucks that EX DP doesn't work well against her. But Sak has a good wakeup pressure game against her so get her once and you can fight back. Take away her ability to FADC Spiral Arrow and drop her vitality by 50, please. Slight disadvantage to disadvantage.

Fei Long
She doesn't have an advantage against him. There aren't any Fei Long's who can do footsies and the things that Fuudo does. It's hard to take damage against Fei unless the Fei player isn't taking you seriously enough. And who the hell thought it was a good idea to give him a command throw? Disadvantage Sak.

Dee Jay
Hmm...I dunno. I've never fought against a solid Dee Jay. Slight advanatage Sak, I think.

Hawk
Gonna go with advantage Sak. Fight it right and it's a hard match for Hawk. This fight will teach you how to properly use her DP.

Sakura
The mirror match. Not to brag but I think I'm the best Sak in the world. Lots of people try to challenge me with their Sak's. But I'm not gonna lose to them.

Rose
Most definitely disadvantage Sak. Personally I put her in my top 5 worst matches for Sak. Her character design just keeps Sak in check, and EX Spiral is strong.

Gen
Probably disadvantage Sak. His ground game is just too strong, and she can't keep him out. His back dash is also good. However he's low vitality, so if you can endure you can press him as well. I'm going to run some sets against Amiyu's Gen.

Dan
Probably not a disadvantage, but a lot harder than you'd think. I think slight advantage, but I don't have a lot of experience with this match so I don't really know.

Guy
Advantage. A running Guy is a pain. Some of his hitboxes are annoying. This is a fight you'll want to fight on the ground.

Cody
This is a good fight. Personally I like this fight a lot. If I have to choose, slight advantage Sak.

Ibuki
I've only fought against Sako, but I'd say slight disadvantage. Both characters have annoying wakeup pressure games. Ibuki's is difficult to read in the middle of the screen, and impossible in the corner (or is he saying unblockable...?). Well, both have unblockables, lol.

Makoto
Advantage if Makoto is using U1, slight disadvantage if U2. What makes it a disadvantage is that Sak doesn't have a safe option against either Karakusa or Tsurugi. You can lose to any Makoto. Mak can escape the corner with U2 then you can't do anything to her.

Dudley
Don't have much experience with this, but I think it's advantage Sak. But sometimes you'll lose on the wakeup game. It's pretty much paper/rock/scissors.

Adon
Definitely disadvantage. He's in the worst 5. It's hard to fight against a clean, streamlined Adon. Sak can hit powerful combos against him so you have a chance. Who the hell thought of making his stand roundhouse two hit and giving Jaguar Kick armor break?!

Hakan
Hmm...don't really know, but advantage Sak? Don't have a lot of experience, so I have no clue, lol.

Juri
A lot of people call this advantage Sak, but really? If she has one it's only slight. It's a pain-in-the-ass fight for both, but Juri can lose the whole thing on one bad call. But I don't see that many Juri's losing, so slight advantage.

Yun
Disadvantage. How easily he can take to the skies is a real pain. It's impossible to bait on back dashes and avoid the command throw. Kazunoko said it best - Yun's a very easy character to use. His dive kick is way too fast.

Yang
Slight advantage. It's a good fight. But the difference in damage output is just terrible. His dive kick and mk are a pain. And of course the command throw.

E.Ryu
Both have vicious wakeup pressure games in the corner. Personally I think this is a good fight. They both can lose in an instant. I'd say a slight advantage for Sak.

Oni
Both again have great wakeup pressure games in the corner. If you're not used to this fight he can kill you in an instant. I'd say even or a slight advantage.

And that's all of them! But Sak is a great practical-use character, so advantages and disadvantages don't matter that much. This is just my opinion, so naturally it'll be different from everyone else's, so don't get too worked up over it.

And the gameplay strategies and matchups are still changing, so yeah.